| Loss | Charles Oliveira | UFC 326: Holloway vs. Oliveira 2 | 7 March 2026 | Decision - Unanimous, R5 5:00 decision |
| Win | Dustin Poirier | UFC 318: Holloway vs. Poirier 3 | 19 July 2025 | Decision decision |
| Win | Arnold Allen | UFC on ESPN 44: Holloway vs. Allen | 15 April 2023 | Decision decision |
| Loss | Alexander Volkanovski | UFC 276: Adesanya vs. Cannonier | 2 July 2022 | Decision decision |
| Win | Yair Rodriguez | UFC on ESPN+ 55: Holloway vs. Rodriguez | 13 November 2021 | Decision decision |
| Win | Calvin Kattar | UFC on ABC 1: Holloway vs. Kattar | 16 January 2021 | Decision decision |
| Loss | Alexander Volkanovski | UFC 251: Usman vs. Masvidal | 12 July 2020 | Decision decision |
| Loss | Alexander Volkanovski | UFC 245: Usman vs. Covington | 14 December 2019 | Decision decision |
| Win | Frankie Edgar | UFC 240: Holloway vs. Edgar | 27 July 2019 | Decision decision |
| Loss | Dustin Poirier | UFC 236: Holloway vs. Poirier 2 | 13 April 2019 | Decision decision |
| Win | Ricardo Lamas | UFC 199: Rockhold vs. Bisping 2 | 4 June 2016 | Decision decision |
| Win | Jeremy Stephens | UFC 194: Aldo vs. McGregor | 12 December 2015 | Decision decision |
| Win | Cole Miller | UFC Fight Night 60: Henderson vs. Thatch | 14 February 2015 | Decision decision |
| Loss | Conor McGregor | UFN 26: Shogun vs. Sonnen | 17 August 2013 | Decision decision |
| Loss | Dennis Bermudez | UFC 160: Velasquez vs. Bigfoot 2 | 25 May 2013 | Decision decision |
| Win | Leonard Garcia | UFC 155: Dos Santos vs. Velasquez II | 29 December 2012 | Decision decision |
| Win | Pat Schilling | TUF 15 Finale: The Ultimate Fighter 15 Finale | 1 June 2012 | Decision decision |